Multiplexing Surface Enhanced Raman Spectroscopy of biomarkers

Micro array based assay recognizing disease biomarkers (Wilms tumor gene – green curve, multidrug resistance protein – red curve) and housekeeping gene expression  (blue curve).

[Reprinted with permission from S. Picciolini, D. Mehn, C. Morasso, R. Vanna, M. Bedoni, P. Pellacani, G. Marchesini, A. Valsesia, D. Prosperi, C. Tresoldi, F. Ciceri, F. Gramatica, Polymer Nanopillar – Gold Arrays as Surface-Enhanced Raman Spectroscopy Substrate for the Simultaneous Detection of Multiple Genes, Acs Nano 8(10) (2014) 10496-10506. Copyright 2014 American Chemical Society]